With the launch of the FDA’s Project Optimus, and the evolving clinical pharmacology guidelines for ADCs, the need to identify an optimal clinical dose that balances safety with efficacy has never been more evident.

Bringing together a focused audience of clinical pharmacology, PK, pharmacometrics, modelling, and bioanalysis specialists, the 2^nd ADC Pharmacokinetics & Clinical Pharmacology Summit returns to Boston December 9-11, 2025.

• Investigate non-traditional payloads and bispecific ADCs to understand how unique PK properties influence clinical outcomes with AstraZeneca & Tavotek
• Explore dose optimization and adjustment through modelling and simulation, with Astellas
• Join Abbvie & Daiichi Sankyo to use bioanalytical methods to assess structural integrity and DAR for deeper insights into drug clearance
• Apply QSP platforms with Novartis to rigorously evaluate the predictive value of computational modelling
• Leverage AI and enhance ADME parameter understanding with Sutro Biopharma & University at Buffalo

See the event guide: https://ter.li/vrojuh