Roche launches DISCOVERY Teal HRP kit to advance tissue-based cancer research
Roche announced the launch of the DISCOVERY Teal HRP kit, the newest addition to the comprehensive collection of modular-based detection kits to identify and profile biomarkers and cell populations in tissue-based research.
DISCOVERY Teal HRP (horseradish peroxidase) kit can be used in combination with other detection kits, expanding the multiplexing capability of both immunohistochemistry (IHC) and in situ hybridization (ISH) by providing a distinct color that contrasts with other chromogens. DISCOVERY Teal HRP complements chromogens including DISCOVERY Yellow, DISCOVERY Purple and DISCOVERY Red, providing a variety of chromogens to choose from for multiplexing up to six biomarkers simultaneously.
The innovative DISCOVERY Teal HRP is translucent and can form a third color when overlapping with another chromogen, a feature that is important in research. This unique property enables researchers to analyze the co-localization of multiple biomarkers through the spatial overlapping of two signals in the context of tissue.
“By expanding the choice of detection tools, we provide the research community with increased flexibility to investigate the presence of multiple biomarkers using just a single slide,” said Ann Costello, Head of Roche Tissue Diagnostics. “Our customers are very excited with the new DISCOVERY Teal HRP chromogen because of its outstanding staining quality which allows them to push the boundaries of biomarker research.”
“Having used the DISCOVERY Teal HRP kit in our lab, we find it to be robust and easy to use,” said Pat Pramoonjago, Technical Director, University of Virginia Biorepository & Tissue Research Facility. “It produces a stain that is clear and beautiful.”
Roche’s DISCOVERY Teal HRP kit is supplied in ready-to-use dispensers and provides a stable staining signal during alcohol dehydration. It can be fully automated on the DISCOVERY ULTRA system.
Image: Skin tissue at 20X magnification using Roche’s DISCOVERY Teal HRP (Source: Roche)