The 5^th Next Generation Gene Therapy Vectors Summit

Recent announcements from major pharmaceutical companies scaling back their AAV gene therapy pipelines have raised concerns across the field. However, this is not the end. It is an opportunity to reset, refocus, and rise to the challenge. While issues such as liver toxicity, pre-existing antibodies, and high manufacturing costs remain significant, so too does the unmatched potential of AAV vectors. From their ability to cross the blood-brain barrier to delivering single-stranded DNA for single-dose cures, AAV continues to offer enormous therapeutic promise.

The 5th Next Generation Gene Therapy Vectors Summit returns to Boston this September to spotlight the scientists and leaders who are continuing to innovate in vector design. This meeting is designed for those who understand that strategic setbacks can often pave the way for transformative breakthroughs, as we saw in the early development of ADCs.

Over the course of 3 days, the summit will bring together experts in vector engineering, translational science, and clinical development to explore how the field can advance in a more refined and resilient direction. Attendees will hear from thought leaders such as Daniel Cohen (Spark Therapeutics), Eric Kelsic (Dyno Therapeutics), Jorge Santiago-Ortiz (Apertura Gene Therapy), Lolita Petit (Coave Therapeutics), Ralf Schmid (Novartis), and Roxanne Croze (4D Molecular Therapeutics).

The program will explore the latest innovations in capsid engineering, novel strategies to overcome immune responses, scalable systemic delivery technologies, and key clinical insights that can shape future development pipelines.

Whether your focus is vector optimization, CMC, or clinical translation, this summit provides a valuable opportunity to connect with the experts and technologies leading the next phase of gene therapy innovation. Join the community in Boston this July and help shape a safer, smarter, and more successful future for AAV.

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